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Module of Pharmacology and Pharmacotherapy Module of Chemotherapy B. The first test relates to anatomy and general function of the autnomous nervous system; cholinergic agonists and antagonists; cholinesterase inhibitory drugs; adrenergic agonists and antagonists; pharmacology of neuromuscolar transmission; local anesthetics; drugs affecting uterine motility; drugs used in the treatment of migraine. The grade obtained in the second test (May) allows the students to take the final exam written, without responding to these test subjects, by 30 December of the year in which the test is performed. Antimicrobial agents: Penicillins, Cephalosporins, Other beta-lactam antibiotics, Carbapenems, Quinolones, Macrolides, Aminoglycosides, Vancomycin, Teicoplanin. The topics are dealt with chemotherapy, for those who do not support or do not pass the test in progress, in a separate written test that must be passed before the end of the written examination. Module of Drug Activities There will be a test in progress at the end of the module (January). Pharmacological and pharmacotherapeutic profile of the interactions between drugs and alcohol. During the test it is not allowed the use of support materials such as textbooks, notes, computer media.

The second optional test is focused on durgs acting on endocrine functions. Estrogens, progestins, androgens and their antagonists. Students should enroll in tests in progress by Almaesami. Mechanism of action of different antimicrobial agents. Chloramphenicol, Tetracyclines, Sulfonamides, Trimethoprim-sulfamethoxazole. Drugs used in chemotherapy of tuberculosis and leprosy: Streptomycin, Isoniazid, Ethambutol, Rifampin, Pyrazinamide, Dapsone, Clofamizine. This is valid for five months, after which - if the student fails the written final exam, the test must be re-claimed. The test consists of a written examination with questions (5) with an opened answer. Practical support: Databases and websites available for information and updates regarding drug interactions. Treatment of central nervous system degenerative disorders. The written examination is given as vote of thirty.

Module of Chemotherapy Students who attend classes can take a test in progress on the topics of the program of chemotherapy in April. Antifungal agents: Amphtericin B, Imidazoles and Triazoles, Fluconazole, Griseofulvin, topical antifungal agents. Suggestions to avoid the negative consequences of drugs interactions. The minimum score for admission to the oral is 18/30.

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The aim of this course is the knowledge for mechanisms of drugs action, their use in therapy, the adverse effects and the more important pharmacological interactions.

During the course each class of drug used will be examined.

Students, at the end of this course, are capable to dispense drugs, to mage pharmacovigilance and to form and inform people about the correct use of drugs.

The student will be capable to characterize drug interactions and to evaluate adverse reactions to drugs.

After completing this module, students gain understanding the main pharmacological and pharmacotherapeutic mechanisms of drug interactions.

They are capable to refer to relevant databases and websites, in order to better dispense medicines, to be informed and updated.In addition, students know and are capable to evaluate the suitable experimental approach (in vitro models) for screening, mechanisms of action definition and pharmacological characterization of new drugs. Pharmacodynamic interactions: additive or summation, potentiation, synergism, antagonism (antagonism physiological or functional, pharmacological, pharmacokinetic or biochemical, chemical).Module of Pharmacology and Pharmacotherapy - Teacher: Prof. Bronchodilatators and other agents used in the treatment of asthma. Agents used for control of gastric acidità and treatment of peptic ulcers. Pharmacokinetic interactions (absorption, distribution, metabolism, elimination). Specific topics: Pharmacological and pharmacotherapeutic profile of the most frequent drugs interactions.Santi Spampinato Introduction to pharmacology Elements of Pharmacosurveillance Periferic nervous system and neuromuscolar junction Anatomy and general function of the periferic nervous system Cholinergic agonists and antagonists and cholinesterase inhibitory drugs Adrenergic agonists and antagonists Pharmacology of neuromuscolar transmission Local anesthetics Drugs affecting uterine motility Drugs used in the treatment of migraine Drugs acting at Central nervous system level Anatomy and general functions of the central nervous system General Anesthetics Drugs effective in the therapy of the epilepsies Drugs for Parkinson desease Drugs used in the treatment of psychoses Treatment of depressive disorders Opioids: agonists and antagonists Treatment of the anxiety disorders Treatment of central nervous system degenerative disorders Drug abuse Cardiovascular and renal system Drugs for the treatment of cardiac insufficiency and della ischemia myocardial Antiarrhythmic drugs Drugs acting on the Renin and angiotensin system Antihypertensive agents and the drug therapy of hypertension Diuretics Immune system and inflammation Histamine, bradykinin and their antagonist Lipid-derived autacoids: eicosanoids e PAF Nonsteroidal Antiinflammatory drugs Glucocorticoids Immunosuppressive agents and immunostimulants Drugs acting on the blood Hematopoietic agents Anticoagulant – Thrombolytic – Antiplatelet – Antifribinolytic drugs Drugs used in the treatment of anemia Drugs capable to modify plasmatic lipid levels Drugs acting on the bronchial function Bronchodilatators and other agents used in the treatment of asthma Antitussive agents and mucolitics Drugs affecting gastrointestinal function Agents used for control of gastric acidità and treatment of peptic ulcers Agents used for diarrhea – costipation – Antiemetics and prokinetic agents Hormones and hormone antagonists Hypothalamic and pituitary hormones Estrogens, progestins, androgens and their antagonists Pancreatic hormones – oral hypoglycemic agents Agents affecting calcification and bone turnover Thyroid and antithyroid drugs Module of Chemotherapy - Teacher: Dr. Antimicrobial agents: Penicillins, Cephalosporins, Other beta-lactam antibiotics, Carbapenems, Quinolones, Macrolides, Aminoglycosides, Vancomycin, Teicoplanin. Pharmacodynamic interactions: additive or summation, potentiation, synergism, antagonism (antagonism functional, pharmacological, pharmacokinetic, chemical). Pharmacological and pharmacotherapeutic profile of the most frequent drugs interactions. Anticoagulant – Thrombolytic – Antiplatelet – Antifribinolytic drugs. Agents used for diarrhea – costipation – Antiemetics and prokinetic agents. Pharmacotherapeutic profile of positive (clinical indications) and negative (adverse reactions) consequences. Pharmacological and pharmacotherapeutic profile of the interactions between drugs and somefoods.Andrea Bedini Antimicrobial agents: general considerations. Mechanism of action of different antimicrobial agents. Chloramphenicol, Tetracyclines, Sulfonamides, Trimethoprim-sulfamethoxazole. Drugs used in chemotherapy of tuberculosis and leprosy: Streptomycin, Isoniazid, Ethambutol, Rifampin, Pyrazinamide, Dapsone, Clofamizine. Pharmacokinetic interactions (absorption, distribution, metabolism, elimination). Pharmacological and pharmacotherapeutic profile of the interactions between drugs and some foods. Three open questions on the topics of the module of Drug Activity. Pharmacological and pharmacotherapeutic profile of the interactions between drugs and alcohol. Databases and websites available for information and updates regarding drug interactions.Antifungal agents: Amphtericin B, Imidazoles and Triazoles, Fluconazole, Griseofulvin, topical antifungal agents. Pharmacological and pharmacotherapeutic profile of the interactions between drugs and alcohol. Databases and websites available for information and updates regarding drug interactions. Suggestions to avoid the negative consequences of drugs interactions.

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