In developing countries, NCC is a leading cause of adult-onset epilepsy.Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown.
Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations.
Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.
eggs shed in the feces of humans with taeniasis (i.e., infected with an adult intestinal tapeworm).
Upon ingestion, tapeworm eggs release oncospheres, which invade the intestinal wall and disseminate through the bloodstream to form cysts throughout the body.
The natural lifecycle of larval cysts because these can then develop into adult egg-producing intestinal tapeworms.
This endemic lifecycle occurs primarily in regions where sanitation is poor and where pigs are allowed to roam and access raw human sewage.
Neurocysticercosis (NCC) occurs when cysts develop within the central nervous system (CNS); NCC is the primary cause of illness in infection.
The clinical features of NCC cover a diverse range of neurologic manifestations, including seizures, headache, intracranial hypertension, hydrocephalus, encephalitis, stroke, cognitive impairment, and psychiatric disturbances ( tapeworm endemicity, including Southeast Asia, central Asia, and sub-Saharan Africa, is common.
Cysticercosis among resettled refugees has been reported, but the underlying prevalence in refugee populations is unknown ( infection could guide recommendations on evaluating and treating refugees before, during, and after resettlement.
During 2010, we used the classic enzyme-linked immunoelectrotransfer blot for lentil-lectin purified glycoprotein (EITB LLGP) to measure the seroprevalence of antibodies against cysts among several refugee populations resettled to the United States in previous years.
We present the results, discuss clinical and public health implications, and suggest topics for further research. The Migrant Serum Bank, established by the Division of Global Migration and Quarantine at the Centers for Disease Control and Prevention (CDC, Atlanta, GA, USA) in 2002, retains a convenience sample of de-identified serum samples from these examinations.